Can MDMA Help Women With HSDD?

Can MDMA Help Women With HSDD?

Embarrassment often keeps women from mentioning sexual problems, and stereotypes make it hard to recognize when there is one.

By Adrienne Koziol

Medically Reviewed By Justin Cooke

Last Updated: January 15, 2024


HSDD affects at least 10% of all women, with some studies saying up to 22% experience it continuously. Unfortunately, HSDD is hard to diagnose, partly due to how subjective the symptoms are. One key sign is that the lack of sexual desire causes distress — but what’s problematic for one person may be fine for another. Another issue is that many women think low desire is normal (or even ideal) — especially as they age — and some cultures almost glorify stifled sexuality.

What is HSDD?

In a nutshell, hypoactive sexual desire disorder (HSDD) is a lack of sexual desire lasting more than six months. HSDD is only diagnosed if the lack of libido is causing distress to the individual. Other medical issues also need to be ruled out before an HSDD diagnosis is made. It’s completely possible for a person to have no desire but not have HSDD; it has to really bother the individual, and not just because it upsets their partner.

Is HSDD Really an Issue?

By definition, yes. The woman’s perspective literally dictates whether she has HSDD or not. Women that have trouble with desire, arousal, or sexual pain tend to be less satisfied with their partners and less happy overall.

What Causes HSDD?

Many diseases, mental health issues, and medications can cause low libido, but in order to be diagnosed with HSDD, there can’t be any other obvious cause besides other sexual disorders. Sexual desire is at least partly controlled by inhibitory and excitatory factors. Decreased excitatory activity, increased inhibitory activity, or both could be the reason for an exaggerated lack of desire.

Adaptive Response

Inhibited sexual response could also be the body’s way of protecting the person from a risky or threatening situation; it can be a response to stress and fatigue, relationship problems, learned behaviors, cultural influences, and past trauma.

Culture & Race

A study in 2007 showed a connection between nationality and desire, indicating that cultural and regional factors play a role in sexual desire.

What is MDMA & Can it Really Help HSDD?

MDMA is a drug known for its euphoric and empathogenic effects. Some researchers believe that MDMA could help women with HSDD by increasing feelings of intimacy and reducing inhibitions.

Euphoria & Tactile Stimulation

The euphoric effects of MDMA may enhance feelings of closeness and intimacy, potentially improving sexual experiences for individuals with HSDD.

Confidence & Self Consciousness

MDMA could also reduce feelings of self-consciousness and increase confidence, leading to a more positive outlook on sexuality.

Is MDMA Safe? What Are the Side Effects?

While MDMA has therapeutic potential, it is important to consider its safety profile and potential side effects. Consulting a healthcare professional before using MDMA for HSDD is crucial.

Current Treatments for HSDD

Various treatments are available for HSDD, including cognitive-behavioral therapy (CBT), hormone therapy, and medications. Exploring different options with a healthcare provider can help individuals find the most suitable treatment.

Conclusion: Can MDMA Help Women With HSDD?

MDMA shows promise in potentially helping women with HSDD by enhancing intimacy, reducing inhibitions, and improving overall sexual experiences. Further research is needed to explore the efficacy and safety of MDMA for this purpose.


[1] Reference 1

[2] Reference 2

[3] Reference 3


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