Clorazepate (Tranxene) Fact Sheet & Harm Reduction Guide

Clorazepate (Tranxene) Fact Sheet & Harm Reduction Guide

Clorazepate, commercially known as Tranxene, is a classical 1,4-benzodiazepine with various similarities to other benzodiazepines like diazepam and clonazepam. Its long-acting properties and metabolism into active metabolites make it unique in its class. This comprehensive guide will explore the key aspects of Clorazepate, including its pharmacology, safety profile, dosage equivalency, and harm reduction strategies.

Clorazepate Specs

Status: Approved Common Dosage: 10-20 mg PubChem ID: 2809 CAS#: 23887-31-2

IUPAC Name

7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid

Other Names

Tranxene, Gen-Xene, Tranxilium, Novo-Clopate

Metabolism

Clorazepate rapidly metabolizes into nordiazepam, a primary active metabolite with an extended half-life. Nordiazepam further converts into oxazepam, offering insights into Clorazepate's pharmacokinetics.

How Does Clorazepate Work?

Clorazepate exerts its effects by potentiating GABA-A receptor activity, leading to neuronal inhibition. Understanding its mechanism of action is crucial in comprehending the therapeutic actions of Clorazepate.

Clorazepate Harm Reduction

Explore practical tips for minimizing risks associated with Clorazepate use, including safe dosage practices, recognizing side effects, and seeking professional guidance for withdrawal management.

Clorazepate FAQs

Common questions about Clorazepate's protein binding values, available formulations, and references provide additional insights into this benzodiazepine.

Conclusion

Clorazepate, as a benzodiazepine, offers unique pharmacological properties and clinical uses. Understanding its profile and implementing harm reduction strategies are essential for safe and effective usage. By leveraging the information presented in this guide, individuals can make informed decisions regarding Clorazepate use.

Call to Action

Interested in learning more about Clorazepate and its pharmacology? Explore additional resources and professional guidance to enhance your knowledge and promote safe medication practices.

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