Understanding Metaclazepam (Talis): Dosage, Safety, and Natural Alternatives

Introduction to Metaclazepam (Talis)

Metaclazepam, sold under the brand name Talis, is a benzodiazepine drug used for its anxiolytic and muscle-relaxant properties. In this article, we will delve into the various aspects of Metaclazepam, including dosage recommendations, safety considerations, and natural alternatives.

Metaclazepam Specs

Status: Approved πŸ‡·οΈ
Common Dosage: 5–20 mg
PubChem ID: 71272
CAS#: 84031-17-4


Metaclazepam is metabolized in the liver through demethylation into an active metabolite called N-desmethylmetaclazepam.

Dosage of Metaclazepam

The recommended dose of Metaclazepam is 15 mg per day, with the option to increase it up to 30 mg per day. It's crucial to be cautious of the potential side effects that may arise with higher doses, such as sedation and breathing problems.

How Does Metaclazepam Work?

Metaclazepam, like other benzodiazepines, functions by enhancing the action potential of nerve cells, resulting in decreased anxiety levels and muscle relaxation. It binds to benzodiazepine receptors and increases sensitivity to the neurotransmitter GABA, facilitating relaxation.

Is Metaclazepam Safe?

While Metaclazepam can be effective for anxiety and muscle tension, it's essential to be aware of potential risks and side effects associated with its use. Consultation with a healthcare provider is advised before starting or adjusting the medication.

Natural Alternatives to Benzodiazepines

For individuals seeking natural alternatives to benzodiazepines like Metaclazepam, several options may offer relief for anxiety and muscle tension. These include Kava, Lavender, Valerian Root, GABA Supplements, and Chamomile. Incorporating these natural remedies into your routine may provide a gentler approach to managing symptoms.


Metaclazepam, marketed as Talis, presents an option for individuals seeking relief from anxiety and muscle-related issues. Understanding its dosage, metabolism, and mechanism of action is key to its safe and effective use. Consider exploring natural alternatives alongside medical guidance for a holistic approach to well-being.

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