Who Should Avoid Ketamine Therapy and Why: A Comprehensive Guide

Ketamine Therapy: Who Isn’t a Good Fit?

Before jumping on the ketamine bandwagon, make sure you’re not at risk for serious complications.

Who Isn’t Suitable for Ketamine Therapy?

First of all, nobody should attempt ketamine therapy without consulting a qualified health professional first. Good clinics will complete thorough medical exams and review your entire medical history long before administering the first dose of ketamine. Certain heart, liver, and kidney conditions could be dangerous if used in combination with ketamine. A comprehensive check with a psychiatrist is also important, as ketamine might not be suitable for those with conditions like schizophrenia or psychosis.

Conditions to Avoid Ketamine Therapy:

  • A history or family history of schizophrenia or psychosis
  • Cardiovascular issues
  • Bladder, kidney, or liver disease
  • Substance abuse disorder
  • Pregnancy or nursing
  • Allergies to ketamine or related substances

Ketamine Side Effects

Ketamine has been used for over fifty years, and its side effects are well known. Some common side effects include lapses in memory, panic attacks, nausea/vomiting, increased blood pressure, and more. The biggest risk of ongoing ketamine therapy is bladder and kidney damage due to a metabolic byproduct of ketamine.

Known Side Effects of Ketamine:

  • Lapses in memory
  • Panic attacks
  • Nausea/vomiting
  • Increased blood pressure
  • Bladder or kidney pain

Who Is a Good Candidate for Ketamine Therapy?

Ketamine is typically given to individuals with treatment-resistant symptoms, meaning they have exhausted other treatment options without relief. For example, Spravato intranasal spray, the only FDA-approved ketamine treatment, is...

Off-Label Uses for Ketamine

In addition to its approved uses, ketamine is also being explored for off-label purposes, such as managing chronic pain or certain mental health conditions.

What to Consider Before Ketamine Therapy

  1. Ketamine Therapy Is Expensive
  2. Getting Access to Ketamine
  3. Ketamine Is Not A Quick Solution
  4. The Ketamine Experience Can Be Terrifying
  5. Set & Setting Are Critical

FAQs: Ketamine Therapy

  • Is Ketamine Addictive?
  • Is Ketamine Safe?
  • How Much Does Ketamine Cost?


Ketamine therapy offers hope to many individuals struggling with various conditions, but it is crucial to understand who may not be suitable candidates for this treatment. By considering the risks and benefits, individuals can make informed decisions about pursuing ketamine therapy.

Call to Action

If you are considering ketamine therapy, consult with a qualified healthcare professional to assess your eligibility and discuss the potential benefits and risks associated with this treatment option.

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